Contents

Client Citation Analysis

Engineered detection zone to enhance color uniformity on paper microfluidics fabricated via Parafilm®-heating-laser-cutting

This study presents a Parafilm®-laminated paper microfluidics fabrication workflow and engineered detection zones that improve the color uniformity of a glucose assay, and uses water contact-angle measurements to evaluate whether the laser ablation step affects Parafilm® hydrophobicity.

At-a-Glance Summary

Dropometer attribution in the paper

Water contact angle was assessed using Dropometer (Droplet Lab) in the device characterization methods.

How the contact-angle data were used in the study

The contact-angle comparison was used to investigate whether laser ablation of the paper alters the hydrophobicity of the Parafilm® layer used in the fabrication method, with results presented as a before/after comparison.

Replication / reliability statement

Figure 3A reports contact-angle values with (n = 3).

Paper Details

Title
Engineered detection zone to enhance color uniformity on paper microfluidics fabricated via Parafilm®-heating-laser-cutting
Authors
Seyed Hamid Safiabadi Tali; Hasti Hajimiri; Zubi Sadiq; Sana Jahanshahi-Anbuhi
Journal
Sensors and Actuators: B. Chemical
Year
2023
Volume
380
Pages / Article
133324
15.6
Scopus metrics (Elsevier / Scopus rating 2024)
CiteScore 2024
Scopus metrics (Elsevier / Scopus rating 2024)
CiteScore subject ranks (CiteScore 2024)
  • Q1 — Physics and Astronomy: Instrumentation (4/174)
  • Q1 — Chemistry: Analytical Chemistry (6/160)
1.332
Scopus metrics (Elsevier / Scopus rating 2024)
SNIP 2024
1.509
Scopus metrics (Elsevier / Scopus rating 2024)
SJR 2024
7.7
Journal Impact Factor (Clarivate JCR)
Journal Impact Factor (JCR )
Journal Impact Factor (Clarivate JCR)
5-Year Impact Factor
Journal Impact Factor (Clarivate JCR)
JCR category rank

What Was Measured

Primary surface / interfacial measurement

Water contact angle of (i) a pristine Parafilm® sheet and (ii) the Parafilm® layer after laser ablation of the paper.

Supporting measurements

Device characterization included laminated-paper thickness measurements, optical microscopy of the cross-sectional structure, and image/video-based measurements (with ImageJ) of barrier/channel widths and flow speed using dye solutions in HPLC water. Relative humidity and temperature were recorded during flow-speed measurements.

Instruments Mentioned

Water contact angle

Dropometer (Droplet Lab)

Thickness

Micrometer (Mitutoyo, Cat. No. 293–832–30)

Laser ablation

CO₂ laser cutter (Universal Laser Systems, VLS 2.30DT with a 2.0 lens)

Cross-sectional imaging

Optical microscope (Westover Scientific)

Width/flow image analysis

ImageJ

Humidity & temperature logging

Thermo-hygrometer (Govee Inc.)

Data analysis

MS Excel 2019

Lamination heating

Laboratory oven (Thermo Scientific, Cat. No. 11-475-152)

Role of the Dropometer

The authors used Dropometer (Droplet Lab) to measure water contact angle on Parafilm® surfaces as a before/after comparison: a pristine Parafilm® sheet versus the Parafilm® layer following laser ablation of the paper from Parafilm®-laminated paper. For the post-ablation measurement, a 2.5 × 2.5 cm paper area was completely ablated, and the contact angle was measured on the exposed Parafilm® layer.

In the paper’s workflow, this Dropometer-based comparison supports the fabrication discussion by checking whether the laser ablation step used in the PHLC process affects Parafilm® hydrophobicity.

Bring This Measurement Into Your Lab

If you need water contact angle checks on laminated or laser processed films, we can show you the same contact angle workflow on your samples.

Method Snapshot

Method Snapshot Table

Measurement series (Dropometer-relevant) Surface tested Sample preparation (as described) Output reported Instruments Conditions Figures
Baseline wettability Pristine Parafilm® sheet Parafilm® sheet measured directly Water contact angle = 108 ± 5° Dropometer (Droplet Lab) - Fig. 3A
Post-processing wettability Parafilm® layer after paper laser ablation 2.5 × 2.5 cm paper area completely ablated from Parafilm®-laminated paper; contact angle measured on ablated area on Parafilm® layer Water contact angle = 109 ± 5° Dropometer (Droplet Lab) - Fig. 3A

Key Findings

Before/after hydrophobicity comparison

Water contact angle was measured on a pristine Parafilm® sheet and on the Parafilm® layer after laser ablation of the paper to evaluate whether the ablation step affects Parafilm® hydrophobicity.

Nearly identical contact-angle values

The reported contact angles were 108 ± 5° (pristine Parafilm®) and 109 ± 5° (Parafilm® after laser ablation of the paper), presented in Figure 3A.

Interpreted as minimal wettability change under the chosen laser settings

The authors discuss that laser ablation may alter surface roughness and wettability depending on settings and material, and they suggest the observed similarity in wettability is possibly due to using laser settings intended to cut the paper with minimal impacts on Parafilm®.

Dropometer measurement integrated into device characterization

In the characterization section, the Dropometer-based contact-angle measurement appears alongside thickness measurements, optical microscopy, and channel/barrier characterization used to describe the fabricated µPAD structure and dimensions.

Figures & Visuals

What it shows

Side-by-side contact-angle images and values comparing unmodified Parafilm® versus Parafilm® after laser cutting/ablation of the paper (reported with n = 3).

What it shows

Top-view and cross-sectional microscopic images illustrating the laminated device structure and the hydrophobic barrier / hydrophilic channel geometry that accompanies the contact-angle characterization.

What it shows

A schematic of the PHLC process showing lamination by oven heating followed by CO₂ laser ablation of patterns on the paper side.

Why It Matters

Parafilm® serves as the hydrophobic component in the paper-lamination approach used to fabricate the µPADs in this study. The Dropometer-based water contact-angle measurements provide a direct check on Parafilm® wettability before and after the laser ablation step that patterns the paper side.

Within the authors’ fabrication discussion, the contact-angle comparison supports their assessment of how the chosen laser-ablation settings interact with the laminated Parafilm® layer during device fabrication.

Expert Perspective

Expert Perspective

Wettability is set by the top five to ten ångström of a surface — what the liquid actually sees. It doesn't matter what lies beneath; that outermost layer is what you are really measuring.

Dr Alidad Amirfazli

Professor, Department of Mechanical Engineering, York University, Co-founder and Scientific Advisor, Droplet Lab

Practical Takeaways

Use a before/after contact-angle check for laser-processing steps

The study measures water contact angle on pristine Parafilm® and after paper laser ablation to assess how the ablation step relates to Parafilm® hydrophobicity.

Match the “after” surface to the processed region

The post-ablation contact angle is measured on the Parafilm® layer exposed by completely ablating a 2.5 × 2.5 cm paper area from the laminated substrate.

Report the contact-angle values alongside the fabrication context

The paper presents the contact-angle comparison in Figure 3A as part of the device characterization narrative around the PHLC fabrication workflow.

Include replication for the contact-angle comparison

Figure 3A reports the contact-angle values with (n = 3).

FAQ

Frequently Asked Questions

What did the Dropometer measure in this study?

The authors used a Dropometer (Droplet Lab) to measure the water contact angle of a pristine Parafilm® sheet and of the Parafilm® layer exposed after laser ablation of the paper. For the second measurement, a 2.5 × 2.5 cm area of paper was completely ablated from the Parafilm® laminated paper before the angle was measured on the exposed Parafilm®.

What contact angle values were reported?

The paper reports a water contact angle of 108 ± 5° for pristine Parafilm® and 109 ± 5° for Parafilm® after laser ablation of the paper, with n = 3 (Fig. 3A). The authors conclude that the hydrophobicity of Parafilm® after ablation was similar to that of the pristine sheet.

What does the result mean for the fabrication method?

The authors suggest the wettability of Parafilm® did not significantly change, possibly because the laser settings were chosen to cut the paper with minimal impact on the Parafilm®. They note that laser ablation can alter surface roughness and wettability depending on the settings and material, so the result applies to the conditions used in this study; surface roughness itself was not measured in the paper.